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Found 15815 articles
Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition.
Genetic amplification of wild-type RAS was recurrent mechanism of resistance.
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03/15/17
Association between Primary Local Treatment and Non-Prostate Cancer Mortality in Men with Non-Metastatic Prostate Cancer.
Patients treated with radiotherapy also had an increased risk of cardiovascular mortality.
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10/27/17
Emergence of High-Avidity Melan-A-Specific Clonotypes as a Reflection of Anti-PD-1 Clinical Efficacy.
Amplification of Melan-A-specific Vß subfamilies undetectable before therapy.
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06/21/17
Prevalence of Delta-like protein 3 expression in patients with small cell lung cancer.
DLL3 expressed in tumor specimens from most patients with SCLC.
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10/22/17
MiR-25-3p promotes the proliferation of triple negative breast cancer by targeting BTG2
Inhibition of BTG2 expression accounted for role of miR-25-3p in TNBC.
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01/08/18
MGAT1 is a novel transcriptional target of Wnt/β-catenin signaling pathway
Overexpression of the β-catenin gene (CTNNB1) increased promoter activity of MGAT1.
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01/08/18
Serum miR-486-5p as a diagnostic marker in cervical cancer: with investigation of potential mechanisms
miR-486-5p directly targeted 3′-untranslated region of tumor-suppressor gene.
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01/09/18
Evaluating the breast cancer predisposition role of rare variants in genes associated with low-penetrance breast cancer risk SNPs
Missense variants in genes associated with low-penetrance breast cancer risk SNPs may contribute some additional risk.
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01/09/18
EZH2 promotes hepatocellular carcinoma progression through modulating miR-22/galectin-9 axis
Restoring galectin-9 expression in miR-22 overexpressing cells strengthened its antitumor effects.
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01/09/18
Inhibition of p38 MAPK activity leads to cell type-specific effects on the molecular circadian clock and time-dependent reduction of glioma cell invasiveness
Phosphorylated p38 MAPK levels were rhythmic in HA glial cells.
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01/10/18
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