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Found 15815 articles
Molecular Determinants of Response to Anti-Programmed Cell Death (PD)-1 and Anti-Programmed Death-Ligand (PD-L)-Ligand 1 Blockade in Patients With Non-Small-Cell Lung Cancer Profiled With Targeted Next-Generation Sequencing.
Targeted NGS accurately estimates TMB.
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01/17/18
Heat shock protein 27 knockdown using nucleotide‑based therapies enhances sensitivity to 5-FU chemotherapy in SW480 human colon cancer cells.
Concurrent treatment with Hsp27 knockdown using apatorsen and 5-FU could be promising therapy for colon cancer.
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07/16/17
Prognostic factors for progression in atypical meningioma.
Wse of PORT associated with improved PFS even in patients who undergo GTR.
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01/20/18
MicroRNA-let-7a regulates cell autophagy by targeting Rictor in gastric cancer cell lines MGC-803 and SGC-7901.
Rictor elaborated its effect on autophagy by phosphorylating Akt and mTOR.
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05/27/17
Circulating small-sized endothelial microparticles as predictors of clinical outcome after chemotherapy for breast cancer: an exploratory analysis.
Post-chemotherapy decrease of VEGFA levels not associated with breast cancer prognosis.
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11/12/17
Piperazine clubbed with 2-azetidinone derivatives suppresses proliferation, migration and induces apoptosis in human cervical cancer HeLa cells through oxidative stress mediated intrinsic mitochondrial pathway.
Elevation of cytochrome c and upregulation of caspase-3 clearly indicated involvement of intrinsic pathway of programmed cell death.
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01/20/18
Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
IFNα transcriptionally induced RIG-I expression in HNSCC cells through STAT1.
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08/03/17
Impact of time to testosterone rebound and comorbidity on the risk of cause-specific mortality in men with unfavorable-risk prostate cancer.
Increasing TTR significantly increased the risk of CVM among men with moderate comorbidity.
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08/24/17
Differential expression of cytokeratin 14 and 18 in bladder cancer tumorigenesis.
Altered CK14 (high) and CK18 (low) expression perhaps early event in bladder cancer tumorigenesis.
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01/20/18
PHD3 controls lung cancer metastasis and resistance to EGFR inhibitors through TGFα.
Opportunities to improve patient treatment by interfering with feedforward signaling mechanisms activated by PHD3 silencing.
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01/10/18
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