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Found 15815 articles
Mutant IDH1 cooperates with ATRX loss to drive the alternative lengthening of telomere (ALT) phenotype in glioma.
Mutant IDH1 initiates telomeric dysfunction and alters DNA repair pathway preferences.
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03/12/18
Kir2.1 interaction with Stk38 promotes invasion and metastasis of human gastric cancer by enhancing MEKK2-MEK1/2-ERK1/2 signaling.
Kir2.1 as independent prognostic indicator for GC patients.
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03/12/18
Berberine decelerates glucose metabolism via suppression of mTOR‑dependent HIF‑1α protein synthesis in colon cancer cells.
Regulation appears to occur via protein synthesis.
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10/13/17
Shorter survival in adolescent and young adult patients, compared to adult patients, with stage IV colorectal cancer in Japan
OS of adolescent and young adult patients significantly worse.
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03/27/18
Depletion of nuclear import protein karyopherin alpha 7 (KPNA7) induces mitotic defects and deformation of nuclei in cancer cells
KPNA7 depletion leads to reorganization of lamin A/C and B1.
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03/27/18
Impact of a behaviorally-based weight loss intervention on parameters of insulin resistance in breast cancer survivors
Participants who achieved ≥5% weight loss had significantly lower fasting insulin.
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03/27/18
Erlotinib treatment after platinum-based therapy in elderly patients with non-small-cell lung cancer in routine clinical practice – results from the ElderTac study
Erlotinib represents suitable palliative treatment option in further therapy lines for elderly patients.
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03/27/18
FOLFIRI plus panitumumab in the treatment of wild-type KRAS and wild-type NRAS metastatic colorectal cancer
First-line FOLFIRI plus panitumumab associated with favourable efficacy.
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03/27/18
The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells
Palbociclib exerted cytostatic effects in Rb-positive TNBC cells.
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03/27/18
Prognostic value of long non-coding RNA BLACAT1 in patients with papillary thyroid carcinoma
Low plasma BLACAT1 expression correlated with lymph node metastasis.
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03/27/18
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