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Found 15815 articles
Enhanced efficacy of histone deacetylase inhibitor combined with bromodomain inhibitor in glioblastoma
Combination of panobinostat with JQ1 or OTX015 results in stronger repression of GBM-associated oncogenic genes.
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10/01/18
Breast cancer survival predicted by TP53 mutation status differs markedly depending on treatment
Wild-type breast cancer cells that were made senescent by doxorubicin treatment were sensitive to tamoxifen.
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10/01/18
Efficacy of anti-PD-1/PD-L1 antibodies after discontinuation due to adverse events in non-small cell lung cancer patients (HANSHIN 0316)
Median PFS after discontinuation not reached for partial response.
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10/03/18
PD-L1/PD-1 crosstalk in colorectal cancer: are we targeting the right cells?
Addition of an α-PD-1 antibody restored lymphocyte proliferation.
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10/03/18
Engrailed-2 (EN2) – a novel biomarker in epithelial ovarian cancer
EN2 positive high-grade serous ovarian cancer patients had shorter PFS.
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10/03/18
Tumor-derived exosomes induce N2 polarization of neutrophils to promote gastric cancer cell migration
Increased HMGB1 expression associated with poor prognosis.
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10/06/18
Identifying patterns of care for elderly patients with non-surgically treated stage III non-small cell lung cancer: an analysis of the national cancer database
CCRT delivered in significantly smaller proportion of elderly.
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10/05/18
Acidic microenvironment plays a key role in human melanoma progression through a sustained exosome mediated transfer of clinically relevant metastatic molecules
Proteins enriched in acidic exosomes significantly correlating with poor prognosis.
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10/05/18
A new ALK isoform transported by extracellular vesicles confers drug resistance to melanoma cells
Nw mechanism of acquired drug resistance involving activation of novel truncated form of ALK.
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10/05/18
Maternal breast cancer risk in relation to birthweight and gestation of her offspring
Risk significantly raised in mothers of high birthweight first-born.
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10/05/18
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