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Found 15807 articles
LKB1 regulates PRMT5 activity in breast cancer.
Point mutation of PRMT5 T139/144 to A139/144 drastically decreased its methyltransferase activity.
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08/27/18
LPA4-mediated vascular network formation increases the efficacy of anti-PD-1 therapy against brain tumors.
Effects of LPA on vascular structure and function apply not only to chemotherapy, but also immunotherapy.
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10/05/18
Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway
Andro could effectively inhibit activity of p300 histone acetyltransferase (HAT).
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10/12/18
Efficacy and safety of concurrent anti-Cancer and anti-tuberculosis chemotherapy in Cancer patients with active Mycobacterium tuberculosis : a retrospective study
Concurrent chemotherapy is effective and safe.
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10/12/18
Clinical outcomes of image-guided proton therapy for histologically confirmed stage I non-small cell lung cancer
IGPT appears to be effective and well tolerated for all patients with stage I NSCLC.
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10/11/18
Molecular profiling of hormone receptor-positive, HER2-negative breast cancers from patients treated with neoadjuvant endocrine therapy in the CARMINA 02 trial (UCBG-0609)
Hotspot mutations detected in 3.4% of treatment-naive tumors.
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10/11/18
Validity and prognostic significance of sperm protein 17 as a tumor biomarker for epithelial ovarian cancer: a retrospective study
Sp17 expression limited in other benign and non-epithelial malignant neoplasms.
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10/11/18
Consistent and reproducible cultures of large-scale 3D mammary epithelial structures using an accessible bioprinting platform
cells from individual prints interact to form structures with a contiguous lumen.
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10/10/18
Genomic analysis of DNA repair genes and androgen signaling in prostate cancer
Inhibition of DNA repair enzyme MRE11 with small molecule mirin inhibits androgen-dependent growth of prostate cancer cells.
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10/10/18
Regulation of Sox2 and stemness by nicotine and electronic-cigarettes in non-small cell lung cancer
Findings shed light on novel molecular mechanisms underlying pathophysiology of smoking-related lung cancer.
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10/15/18
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