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Found 15807 articles
The oncogene KRAS promotes cancer cell dissemination by stabilizing spheroid formation via the MEK pathway
MEK inhibitor, trametinib, suppressed spheroid formation in 3D culture of ID8-KRAS cells.
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12/03/18
Neutrophils to lymphocytes ratio as a useful prognosticator for stage II colorectal cancer patients
Dismal prognostic effect of NRL magnified in Stage II CRC patients.
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12/03/18
Performance of a DNA methylation marker panel using liquid-based cervical scrapes to detect cervical cancer and its precancerous stages
DNA methylation analysis of cervical scrapes consistently detects cervical cancer.
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12/03/18
The role of matrix metalloproteinase-9 as a prognostic biomarker in papillary thyroid cancer
mRNA and protein levels of MMP-9 had no association with BRAF V600E mutation.
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12/03/18
Influence of afatinib dose on outcomes of advanced EGFR-mutant NSCLC patients with brain metastases
Initiating patients on afatinib 40 mg OD associated with improved PFS.
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12/03/18
CircFAT1 sponges miR-375 to promote the expression of Yes-associated protein 1 in osteosarcoma cells
Mechanistic studies revealed that circFAT1 contains a binding site for the microRNA-375.
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12/04/18
Mutated Von Hippel-Lindau-renal cell carcinoma (RCC) promotes patients specific natural killer (NK) cytotoxicity
IL-2 activated NKs induced higher CD107a exposure in presence of RCC autologous tumor cells.
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12/04/18
Co-occurring KRAS mutation/LKB1 loss in non-small cell lung cancer cells results in enhanced metabolic activity susceptible to caloric restriction: an in vitro integrated multilevel approach
Co-occurring KRAS mutation/LKB1 loss in NSCLC cells allowed efficient exploitation of glycolysis and oxidative phosphorylation.
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12/04/18
Alterations in arginine and energy metabolism, structural and signalling lipids in metastatic breast cancer in mice detected in plasma by targeted metabolomics and lipidomics
Late but not early phase of metastasis characterized by different lipid profile pattern in plasma.
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12/04/18
Exploring the efficacy of an electronic symptom assessment and self-care intervention to preserve physical function in individuals receiving neurotoxic chemotherapy
Use of ESRA-C intervention led to less reduction in physical function.
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12/04/18
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