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Found 15790 articles
Molecular and epigenetic profiles of BRCA1-like hormone-receptor-positive breast tumors identified with development and application of a copy-number-based classifier
Individually significant CpGs enriched for enhancer regions.
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01/25/19
p53 controls the plasticity of mammary luminal progenitor cells downstream of Met signaling
Study reveals crosstalk between Met- and p53-mediated signaling pathways.
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01/25/19
Identifying and targeting cancer stem cells in leiomyosarcoma: prognostic impact and role to overcome secondary resistance to PI3K/mTOR inhibition
EZH2 inhibition restored sensitivity to PI3K/mTOR pathway inhibition.
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01/25/19
Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer
CRC patients exhibiting active CRCSC signal showed elevated tumor infiltration of MPO.
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01/25/19
CXCL12/CXCR4 promotes inflammation-driven colorectal cancer progression through activation of RhoA signaling by sponging miR-133a-3p
Negative correlation of miR-133a-3p with RhoA also confirmed in human CRC tissues.
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01/24/19
Intravital imaging reveals systemic ezrin inhibition impedes cancer cell migration and lymph node metastasis in breast cancer
Ezrin expressed at significantly higher levels in lymph node metastases.
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01/24/19
Cell cycle, energy metabolism and DNA repair pathways in cancer cells are suppressed by Compound Kushen Injection
CKI likely acts through effect of multiple compounds on multiple targets.
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01/24/19
Overcoming acquired resistance to HSP90 inhibition by targeting JAK-STAT signalling in triple-negative breast cancer
Inhibition of JAK and HSP90 caused higher induction of apoptosis.
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01/24/19
Cytokine-induced memory-like natural killer cells have enhanced function, proliferation, and in vivo expansion against ovarian cancer cells.
NK cell-based immunotherapy to circumvent immunosuppressive nature.
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09/26/18
Hormonal and reproductive factors and risk of upper gastrointestinal cancers in men: A prospective cohort study within the UK Biobank.
Some evidence that male pattern baldness associated with gastric cancer risk.
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08/18/17
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