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Found 15790 articles
Crosslink between Temozolomide and PD-L1 immune-checkpoint inhibition in glioblastoma multiforme
Additional TMZ treatment led to reduction of PD-L1 expression and JAK/STAT pathway activation.
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02/01/19
Analysis on GENIE reveals novel recurrent variants that affect molecular diagnosis of sizable number of cancer patients
identified 45,933 novel variants with unknown significance unique to GENIE.
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02/01/19
Prevalence of germline mutations in the TP53 gene in patients with early-onset breast cancer in the Mexican population
Patients with TP53 mutations had high-grade and HER2-positive tumors.
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02/01/19
Predictors for use of psychosocial services in patients with metastatic colorectal cancer receiving first line systemic treatment
Use of psychosocial services associated with younger age, higher educational level, presence of more pain.
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02/01/19
miR-205 enhances radiation sensitivity of prostate cancer cells by impairing DNA damage repair through PKCε and ZEB1 inhibition
miR-205-induced suppression of PKCε counteracted radioresistance through impairment of EGFR nuclear translocation.
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02/04/19
CIB1 depletion with docetaxel or TRAIL enhances triple-negative breast cancer cell death
Combination treatments also induced nearly complete death of docetaxel-resistant MDA-MB-436 cells.
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02/04/19
Impact of in vitro driven expression signatures of CD133 stem cell marker and tumor stroma on clinical outcomes in gastric cancers
High CD133 expression signatures were found in intestinal subtypes and low tumor stage GCs.
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02/04/19
Dissimilar patterns of tumor-infiltrating immune cells at the invasive tumor front and tumor center are associated with response to neoadjuvant chemotherapy in primary breast cancer
Presence of DTCs after NACT related to CD4+ infiltration at the TC.
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02/04/19
Kinase inhibitor library screening identifies synergistic drug combinations effective in sensitive and resistant melanoma cells
Combination of a Wee1 and Chk inhibitor showed synergistic killing effects.
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02/06/19
Exosomal miRNA profile as complementary tool in the diagnostic and prediction of treatment response in localized breast cancer under neoadjuvant chemotherapy
Higher levels of exosomal miRNA-21, miRNA-222, and miRNA-155 significantly associated with presence of circulating tumor cells.
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02/06/19
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