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Found 15790 articles
The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells
Ajoene inhibited invasion and migration of both cancer cell lines.
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03/20/19
Trabectedin triggers direct and NK-mediated cytotoxicity in multiple myeloma
Drug-induced cell stress in MM cells led to upregulation of NK activating receptors ligands.
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03/21/19
Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer
Inactivation of ERBB3/PI3K by these therapeutic antibodies insufficient to inhibit ERBB2-amplified breast cancer cells.
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03/21/19
LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy
Morin negatively regulates adhesion and CXCL12-dependent migration of Mec-1.
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03/21/19
Decreased serum carbohydrate antigen 19–9 levels after neoadjuvant therapy predict a better prognosis for patients with pancreatic adenocarcinoma: a multicenter case-control study of 240 patients
Responder group also showed lower risk of hepatic recurrence.
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03/21/19
Comparative sequence analysis of patient-matched primary colorectal cancer, metastatic, and recurrent metastatic tumors after adjuvant FOLFOX chemotherapy
Genes related to intracellular Ca2+ homeostasis were enriched.
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03/21/19
Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cells
Bortezomib, a proteasome inhibitor, especially toxic in PANC-1 cells.
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03/21/19
Hypothyroidism and the risk of breast cancer recurrence and all-cause mortality - a Danish population-based study
No differences seen for all-cause mortality for prevalent or incident hypothyroidism.
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03/22/19
A novel microfluidic device capable of maintaining functional thyroid carcinoma specimens ex vivo provides a new drug screening platform
Microfluidic platform can maintain viability of thyroid tissue slices ex vivo for minimum of four days.
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03/22/19
Interaction between the BAG1S isoform and HSP70 mediates the stability of anti-apoptotic proteins and the survival of osteosarcoma cells expressing oncogenic MYC
BAG1S provides its pro-survival function by serving as cofactor for HSP70 chaperone complex.
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03/22/19
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