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Found 15790 articles
Depletion of PCAT-1 in head and neck cancer cells inhibits tumor growth and induces apoptosis by modulating c-Myc-AKT1-p38 MAPK signalling pathways
c-Myc and AKT1 positively correlate with PCAT-1 expression in HNSCC.
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04/15/19
Relative efficacy of interventions in the treatment of second-line non-small cell lung cancer: a systematic review and network meta-analysis
EGFR tyrosine kinase inhibitors (TKIs) erlotinib and gefitinib showed superior levels of efficacy.
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04/15/19
Glucocorticoid-dependent expression of IAP participates in the protection against TNF-mediated cytotoxicity in MCF7 cells
RU486 significantly inhibited anti-cytotoxic effect of both GCs.
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04/15/19
Neoadjuvant versus definitive chemoradiation in patients with squamous cell carcinoma of the esophagus
Proximal tumor location independently associated with increased risk for local treatment failure.
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04/16/19
Brain metastases in patients with neuroendocrine neoplasms: risk factors and outcome
Screening for brain metastases could be advisable in NEC patients.
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04/16/19
Genome sequencing analysis of blood cells identifies germline haplotypes strongly associated with drug resistance in osteosarcoma patients
Intronic and intergenic hotspot regions from 26 genes significantly associated with relapse.
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04/16/19
Differential expression of androgen receptor variants in hormone-sensitive prostate cancer xenografts, castration-resistant sublines, and patient specimens according to the treatment sequence.
JDCaP-CR2F exhibited elevated AR-v567es expression resulting from genomic deletion.
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10/17/18
Multiple biomarker algorithms to predict epithelial ovarian cancer in women with a pelvic mass: Can additional makers improve performance?
Combination of HE4 and CA125 (i.e. ROMA) achieved an AUC of 91.2%.
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02/26/19
Concurrent Targeting of Glutaminolysis and Metabotropic Glutamate Receptor 1 (GRM1) Reduces Glutamate Bioavailability in GRM1
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Melanoma.
Targeting glutaminolytic glutamate bioavailability effective therapeutic strategy for GRM1-activated tumors.
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05/15/18
Differential expression of tescalcin by modification of promoter methylation controls cell survival in gastric cancer cells.
Silencing of TESC increased MBD1 expression and decreased H3K4me2/3 level.
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10/25/18
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