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Found 15757 articles
RNF43 mutation is associated with aggressive tumor biology along with BRAF V600E mutation in right-sided colorectal cancer.
Right-sided RNF43 mutant-type exhibited significantly worse overall survival than RNF43 wild-type.
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11/14/19
Machine Learning Algorithm Identifies Patients at High Risk for Early Complications After Intracranial Tumor Surgery: Registry-Based Cohort Study.
Pathology and surgery-related (histology, anatomical localization, surgical access) variables better predictors of EPC.
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08/21/18
Therapeutically actionable PAK4 is amplified, overexpressed, and involved in bladder cancer progression.
Combined inhibition of PAK4 and PTK6 may overcome resistance to PAK4.
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10/01/19
Metformin is distributed to tumor tissue in breast cancer patients in vivo: A
11
C-metformin PET/CT study.
Tumor tissue displayed distinct uptake of metformin compared to normal breast tissue.
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02/04/20
CRISPR/CAS9-mediated knockout of Abi1 inhibits p185 Bcr-Abl -induced leukemogenesis and signal transduction to ERK and PI3K/Akt pathways
Abi1 deficiency reduced IL3-independent growth and SDF-1α-mediated chemotaxis.
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04/10/20
Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment
Breast cancer cells localized in close proximity to Endomucin-positive vascular cells.
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04/09/20
Challenges in diagnosis and management of neutropenia upon exposure to immune-checkpoint inhibitors: meta-analysis of a rare immune-related adverse side effect
Median onset of neutropenia 10.5 weeks after first ICI administration.
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04/14/20
GD2 targeting by dinutuximab beta is a promising immunotherapeutic approach against malignant glioma.
ADCC mediated by dinutuximab beta was observed against the majority of GBM cells.
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01/11/20
Increased Risk of Colorectal Cancer in Individuals With a History of Serrated Polyps.
Presence of synchronous adenomas increased risk for CRC.
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09/27/19
Urine Endocannabinoids as Novel Non-Invasive Biomarkers for Bladder Cancer at Early Stage.
Significant variations in expression of three enzymes involved in EC and NAE turnover in bladder cancer.
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02/18/20
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