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Found 16137 articles
The predictive value of PD-1 for the response to immune checkpoint inhibitor therapy in patients with bladder cancer without lymph node metastasis and its association with survival outcomes
High PD-1 expression independent protective factor for PFS.
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08/07/26
NPTXR as a novel therapeutic target: efficacy of antibody-drug conjugates in preclinical tumor models
NPTXR protein highly and consistently expressed in human tissue samples.
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08/07/26
Panel-based next-generation sequencing with copy number variant detection pipeline could increase the detection rate of hereditary colorectal cancer syndrome compared with Sanger sequencing
MSI and MMR IHC results showed strong concordance with molecular findings.
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08/07/26
A phase 1 trial of CD123-directed chimeric antigen receptor T-cell therapy in adults with relapsed/refractory acute myeloid leukemia or blastic plasmacytoid dendritic cell neoplasm
No dose-limiting toxicity, prolonged myelosuppression, or graft-versus-host disease.
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08/07/26
Tumor-infiltrating B cells evolve towards interferon-rich trajectories aligned with immunotherapy in melanoma
Transcriptomic analyses of B cells pointed to upregulated antigen-driven stimulation and BCR signaling.
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08/07/26
CRISPR screens reveal MCT1-driven metabolic escape from SMAD3 inhibition as a therapeutic vulnerability
MCT1 as both metabolic and immunological target.
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08/07/26
Clinical impact of second radiotracer injection after failed lymphoscintigraphy in breast cancer sentinel lymph node biopsy: a retrospective cohort study
SLNB technically equally successful after failed and successful LS.
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08/07/26
Establishment and genomic validation of novel patient-derived xenograft models for drug discovery in gastrointestinal stromal tumor
Importance of comprehensive genomic characterization of PDX models prior to their use in preclinical studies.
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08/10/26
Mode of diagnosis of metastatic breast cancer recurrence and survival: a retrospective study
Trend for improved 1st line PFS in patients diagnosed by screening.
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08/10/26
Micro-CT radiomics reveals the microcalcification-surrounding tissue interface as the diagnostic epicenter of breast microcalcifications
Classification performance remained high.
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08/10/26
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