Treatment of T24 cells with costunolide resulted in a dose-dependent inhibition of cell viability and induction of apoptosis. »
11/26/12

Pioglitazone use is associated with an increased risk of bladder cancer. »
06/27/12

JARID1B plays a role in CRC maintenance. »
09/18/12

ICAM-1 plays an important role in tongue SCC progression. »
06/19/12

KRC-408, a Novel c-Met Inhibitor, Suppresses Cell Proliferation and Angiogenesis of Gastric Cancer. »
11/27/12

Experimental hypoxia does not influence gene expression and protein synthesis of Eph receptors and ephrin ligands in human melanoma cells in vitro. »
01/30/13

β-Blocker use was associated with reduced PCa-specific mortality in patients with high-risk or metastatic disease. »
10/29/12

Recent data suggest that benefit from trastuzumab and chemotherapy might be related to expression of HER2 and estrogen receptor (ESR1). Therefore, we investigated HER2 and ESR1 mRNA levels in core biopsies of HER2-positive breast carcinomas from patients treated within the neoadjuvant GeparQuattro trial. »
02/07/13

TP53 gene mutations can lead to the expression of a dysfunctional protein that in turn may enable genetically unstable cells to survive and change into malignant cells. Mutant p53 accumulates early in cells and can precociously induce circulating anti-p53 antibodies (p53Abs); in fact, p53 overexpression has been observed in pre-neoplastic lesions, such as bronchial dysplasia, and p53Abs have been found in patients with Chronic Obstructive Pulmonary Disease, before the diagnosis of lung and other tobacco-related tumors. »
02/06/13

The long term outcome of advanced sarcoma patients treated with trabectedin outside of clinical trials and the utility of maintenance treatment has not been reported. »
02/06/13