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Found 15774 articles

Activation of MAPK pathways due to DUSP4 loss promotes cancer stem cell-like phenotypes in basal-like breast cancer.

Findings support the evaluation of MEK and JNK pathway inhibitors as therapeutic agents in BLBC. »
08/23/13

Molecular crosstalk between apoptosis and autophagy induced by a novel 2-methoxyestradiol analogue in cervical adenocarcinoma cells

ESE-16, exerts its anti-proliferative effect on the tumorigenic human epithelial cervical (HeLa) cells by sequentially targeting microtubule integrity »
08/27/13

Histone acetyltransferase PCAF Up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling

PCAF overexpression induced cell apoptosis and growth arrest with increased Histone H4 acetylation »
08/27/13

SU6668 suppresses proliferation of triple negative breast cancer cells through down-regulating MTDH expression

SU6668 exposure maybe induces polyploidization, inhibit EMT and influence the expression of MTDH »
08/29/13

Mahanine restores RASSF1A expression by down-regulating DNMT1 and DNMT3B in prostate cancer cells

Mahanine could be a potential therapeutic agent for advanced prostate cancer in men »
08/30/13

Glyceraldehyde-3-phosphate dehydrogenase gene over expression correlates with poor prognosis in non small cell lung cancer patients

GAPDH gene over expression in resected tumor samples an adverse prognostic factor in NSCLC. »
08/29/13

Aberrant septin 9 DNA methylation in colorectal cancer is restricted to a single CpG island

Hypermethylation of SEPT9 in adenoma and CRC specimens is confined to one of several CpG islands and aberrant methylation originates in epithelial cells »
08/30/13

Therapeutic PD-1 Pathway Blockade Augments with other Modalities of Immunotherapy to Prevent Immune Decline in Ovarian Cancer.

PD-1/PD-L1 blockade enhanced the amplitude of tumor immunity by reprogramming suppressive and stimulatory signals »
08/27/13

MiR-215 modulates gastric cancer cell proliferation by targeting RB1.

Up-regulated miR-215 in gastric cancer may influence cell proliferation by targeting RB1 »
12/04/12

Expression of the h19 oncofetal gene in premalignant lesions of cervical cancer: a potential targeting approach for development of nonsurgical treatment of high-risk lesions.

Results suggest that most CIN3 lesions could be targeted by H19-DTA. »
08/13/13

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