H2O2 preferentially affects both the LSC subset and total HL-60 cells without damage normal cells. »
12/23/13

The exposure of skin keratinocytes to Ultraviolet (UV) irradiation leads to Akt phosphorylation at Ser-473, which is important for the carcinogenic effects of excessive sun exposure. The present study investigated the underlying mechanism of Akt Ser-473 phosphorylation by UVB radiation. »
12/24/13

Inhibition of calcium signaling, NFATc1 activation, and ERK1/2 phosphorylation significantly reduced the ability of prostate cancer mediators to stimulate osteoclastogenesis. »
12/26/13

GLTSCR2 functions as a tumor suppressor in prostatic adenocarcinomas. »
04/24/13

Use of PD-1 and Tim-3 blockades with cancer vaccines to stimulate potent antitumor T cell responses. »
12/18/13

SOX2-expressing ovarian CSCs as a mechanism of tumor aggressiveness and therapy resistance in human SOC. »
07/18/13

In NSCLC GLY12Cys mutations, resulting from a codon 12 GGT>TGT substitution, were observed in 44%. »
07/27/13

Increased level of mucosa-associated and internalized E. coli was observed in the tumors compared with normal tissue. »
12/17/13

CDO1/CSA axis using a lentiviral mediated shRNA approach resulted in significant tumor growth inhibition in a glioblastoma mouse model. »
12/20/13

Key role of the small GTPase RhoA in upregulation of Nav1.5 channel expression and tumor aggressiveness. »
09/23/13