Anti-proliferative effects of Res in human colon cancer cells may be mediated by regulating separately PTEN/PI3K/Akt and Wnt/β-catenin signaling. »
01/16/14

HOTAIR expression in cervical cancer tissues was significantly upregulated. »
11/06/13

Primary multidrug resistance network in gastric cancer established. »
01/06/14

Protumorigenic role for CLPTM1L that is critical for Ras-driven lung cancers. »
12/23/13

The androgen receptor (AR) plays a central role in the oncogenesis of different tumors, as is the case in prostate cancer. In triple negative breast cancer (TNBC) a gene expression classification has described different subgroups including a luminal androgen subtype. The AR can be controlled by several mechanisms like the activation of membrane tyrosine kinases and downstream signaling pathways. However little is known in TNBC about how the AR is modulated by these mechanisms and the potential therapeutic strategists to inhibit its expression. »
04/30/14

Correlation between WNT5A expression and angiogenesis marker ESAM. »
04/26/14

TIA proteins can function as long-term regulators of the ACTB mRNA metabolism in mouse and human cells. »
04/27/14

Glucocorticoids (GCs) are often included in the therapy of lymphoid malignancies because they kill several types of malignant lymphoid cells. GCs activate the glucocorticoid receptor (GR), to regulate a complex genetic network, culminating in apoptosis. Normal lymphoblasts and many lymphoid malignancies are sensitive to GC-driven apoptosis. Resistance to GCs can be a significant clinical problem, however, and correlates with resistance to several other major chemotherapeutic agents. »
04/23/14

LAG-3 blockade restored the reduced IFN-γ secretion mediated by melanoma-derived LSECtin. »
04/29/14

SPDEF expression corresponded with bicalutamide growth inhibition and apoptosis induction. »
05/24/13