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Found 15807 articles
GSTP1 promoter methylation is associated with recurrence in early stage prostate cancer.
GSTP1 methylation extent was higher in recurrence cases than in controls.
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04/14/14
Rac1 as a potential therapeutic target for chemo-radioresistant head and neck squamous cell carcinomas (HNSCC).
Tumour tissues revealed increased Rac1 expression.
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02/10/14
An RNAi-based screen reveals PLK1, CDK1 and NDC80 as potential therapeutic targets in malignant pleural mesothelioma.
Malignant pleural mesothelioma (MPM) is an aggressive tumour originating in the thoracic mesothelium. Prognosis remains poor with 9- to 12-month median survival, and new targets for treatments are desperately needed.
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09/03/13
Hsa-miR-31-3p expression is linked to progression-free survival in patients with KRAS wild-type metastatic colorectal cancer treated with anti-EGFR therapy.
Identified 47 genes regulated by hsa-miR-31-3p.
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04/29/14
Overexpression of fatty acid synthase in human gliomas correlates with the WHO tumor grade and inhibition with Orlistat reduces cell viability and triggers apoptosis.
FASN may be a therapeutic target in malignant gliomas.
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10/15/13
Folate intake and the risk of breast cancer: a systematic review and meta-analysis.
Breast cancer does not appear to be associated with folate intake.
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04/10/14
Regulation of apoptosis by long non-coding RNA GAS5 in breast cancer cells: implications for chemotherapy.
Reduced GAS5 expression attenuates apoptosis induction by classical chemotherapeutic agents in breast cancer cells.
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02/13/14
Decreased expression of long noncoding RNA GAS5 indicates a poor prognosis and promotes cell proliferation in gastric cancer
GAS5 could influence gastric cancer cells proliferation, partly via regulating E2F1 and P21 expression.
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05/06/14
Aquaporin 3 Promotes Epithelial-Mesenchymal transition in gastric cancer
AQP3 modulated GC cell proliferation, migration and invasion in vitro, and induced E-cadherin repression.
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05/03/14
Small nucleolar RNA signatures of lung tumor-initiating cells
snoRA42 expression associated with expression of stem cell-core transcription factors in lung TICs.
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05/06/14
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