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Found 15815 articles
HNRNPAB induces epithelial-mesenchymal transition and promotes metastasis of hepatocellular carcinoma by transcriptionally activating SNAIL.
HNRNPAB overexpression, alone or in combination with SNAIL, was found to be a significant independent risk factor.
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03/17/14
KLF5 regulates the integrity and oncogenicity of intestinal stem cells.
Klf5 was indispensable for the integrity and oncogenic transformation of intestinal stem cells.
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03/13/14
Uncontrolled inflammation induced by AEG-1 promotes gastric cancer and is associated with poor prognosis.
AEG-1 can promote gastric cancer progression by a positive feedback TLR4/NF-κB signaling-related mechanism.
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08/06/14
ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency.
Reduced function in the ATR pathway itself provided the strongest synthetic lethal interaction.
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03/24/14
The dynamic range of circulating tumor DNA in metastatic breast cancer
Dynamic range of ctDNA varies substantially in patients.
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08/09/14
PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors
Growth and viability of AR?+?TNBC cell line models is significantly reduced after treatment with PI3K inhibitors.
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08/08/14
Chk1 Inhibition as a novel therapeutic strategy for treating triple-negative breast and ovarian cancers
Chk1 inhibitors V158411, PF-477736 and AZD7762 potently inhibited the proliferation of ovarian cancer cells.
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08/07/14
Cardiac glycosides use and the risk of lung cancer: a nested case–control study
CGs was not associated with an increased risk of lung cancer.
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08/08/14
Detection of infectious organisms in archival prostate cancer tissues
Mycoplasma genitalium DNA was detected in a few samples.
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08/09/14
Elevated levels of plasma D-dimer predict a worse outcome in patients with nasopharyngeal carcinoma
Subgroup analyses indicated that the plasma D-dimer levels could effectively stratify patient prognosis.
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08/10/14
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