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Found 15815 articles
Genes involved in the WNT and vesicular trafficking pathways are associated with melanoma predisposition.
Two new pathways involved in melanoma predisposition.
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04/07/14
Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells.
Malignant cells get extinguished. FASN-expression and FASN-drug-sensitivity.
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06/05/14
Redirection of CD4+ and CD8+ T lymphocytes via a novel antibody-based modular targeting system triggers efficient killing of PSCA+ prostate tumor cells.
Novel PSCA-specific modular system induces activation of both CD4+ and CD8+ T cells leading to secretion of pro-inflammatory cytokines.
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02/21/14
Statin use after radical prostatectomy reduces biochemical recurrence in men with prostate cancer.
Postoperative statin use until 36 months decreased the risk of BCR independently.
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05/14/14
Curcumin induces human SKOV3 cell apoptosis via the activation of Rho-kinase.
Expression of activated caspase-3 was significantly decreased.
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08/15/14
In vivo evidence that secretion of HLA-G by immunogenic tumor cells allows their evasion from immunosurveillance.
Characterized by dampened anti-hβ2m B-cell response.
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07/15/13
Simultaneous NF-κB inhibition and E-cadherin upregulation mediate mutually synergistic anticancer activity of celastrol and SAHA in vitro and in vivo.
Combination of celastrol and SAHA was superior to other combination regimens that rely on a single mechanism.
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01/10/14
SGI-110 and entinostat therapy reduces lung tumor burden and reprograms the epigenome.
Highly significant gene expression changes were seen in key cancer regulatory pathways including induction of p21.
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11/22/13
The role of a Mediterranean diet on the risk of oral and pharyngeal cancer.
Favourable effect of the Mediterranean diet was apparently stronger in younger subjects.
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02/28/14
SOX2 regulates self-renewal and tumorigenicity of stem-like cells of head and neck squamous cell carcinoma.
Ectopic expression of SOX2 induced cell proliferation via cyclin B1 expression.
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03/26/14
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