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Found 15815 articles
Unraveling the Role of Huntingtin in Breast Cancer Metastasis.
Huntingtin (HTT) may inhibit breast tumor dissemination through maintenance of ZO1 at tight junctions.
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11/19/14
Expression and Tissue Distribution of MicroRNA-21 in Malignant and Benign Breast Tissues.
High miR-21 ISH scores were correlated with positive lymph node status.
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05/31/15
Reactive oxygen species production has a critical role in hypoxia-induced Stat3 activation and angiogenesis in human glioblastoma.
Nox4 expression was found to be increased at both mRNA and protein levels in hypoxic glioblastoma cells.
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03/09/15
Glioblastomas require integrin αvβ3/PAK4 signaling to escape senescence.
Glioblastomas are selectively addicted to this pathway as a strategy to evade oncogene-induced senescence.
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08/23/15
Randomized Controlled Study of the Efficacy, Safety and Quality of Life of Low-Dose Bacillus Calmette-Guérin Instillation Therapy for Non-Muscle-Invasive Bladder Cancer.
Low-dose BCG was associated with lower toxicity and higher QOL.
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08/05/15
Tumor microenvironment B cells increase bladder cancer metastasis via modulation of the IL-8/androgen receptor (AR)/MMPs signals.
Blocking the IL-8/AR/MMPs signals partially reversed the infiltrating B cells capacity to increase the BCa cell invasion.
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04/15/15
MiR-124 exerts tumor suppressive functions on the cell proliferation, motility and angiogenesis of bladder cancer by fine-tuning UHRF1.
UHRF1, an epigenetic factor, is implicated in various cellular processes of tumorigenesis.
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08/28/15
Metformin represses androgen-dependent and androgen-independent prostate cancers by targeting androgen receptor.
Metformin down-regulated full-length AR protein in LNCaP cells.
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02/19/15
Low numbers of tryptase+ and chymase+ mast cells associated with reduced survival and advanced tumor stage in melanoma.
Serine proteinases of mast cells may be protective in the pathogenesis of melanoma.
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08/29/15
Detection of the HE4 protein in urine as a biomarker for ovarian neoplasms: Clinical correlates.
HE4 values in urine also became positive in advance of clinical recurrence in several women.
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02/13/15
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