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Found 15815 articles
HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers
Ricolinostat (ACY1215), a leading HDAC6 inhibitor, efficiently controls IBC cell proliferation.
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12/08/15
High-grade serous ovarian cancer cell lines exhibit heterogeneous responses to growth factor stimulation
Response is dependent on intrinsic qualities of the tumor cell rather than the growth factor.
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12/07/15
Exosomal particles secreted by prostate cancer cells are potent mRNA and protein vehicles for the interference of tumor and tumor environment.
Analysis of mRNA and protein composition of exosomes exhibited a wide range of mRNA and protein species.
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09/18/15
Phase 1b Safety Study of Farletuzumab, Carboplatin and Pegylated Liposomal Doxorubicin in Patients with Platinum-Sensitive Epithelial Ovarian Cancer.
This multicenter, single-arm study enrolled patients with platinum-sensitive EOC.
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09/08/15
Periodic acid-Schiff-positive loops and networks as a prognostic factor in oral mucosal melanoma.
PAS-positive loops and networks have a significant prognostic value.
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12/05/15
Suppression of AKT Potentiates Synergistic Cytotoxicity of Apigenin with TRAIL in Anaplastic Thyroid Carcinoma Cells.
Apigenin synergizes with TRAIL through regulation of Bcl2 family proteins.
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12/06/15
Control of PD-L1 expression by oncogenic activation of the AKT/mTOR pathway in non-small cell lung cancer.
Data suggest oncogenic activation of the AKT/mTOR pathway promotes immune escape by driving expression of PD-L1.
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12/06/15
Phosphatidylinositol Derivatives Induce Gastric Cancer Cell Apoptosis by Accumulating AIF and AMID in the Nucleus.
Both diDCP-LA-D-PI and diDCP-LA-L-PI induced caspase-independent apoptosis of MKN28 cells.
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12/06/15
Dexamethasone alone and in combination with desipramine, phenytoin, valproic acid or levetiracetam interferes with 5-ALA-mediated PpIX production and cellular retention in glioblastoma cells.
Medications given before and during surgery may interfere with PpIX accumulation in malignant cells.
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08/04/15
RhoA is associated with invasion and poor prognosis in colorectal cancer.
Patients with higher RhoA expression had a significantly poorer 5-year survival rate after surgery.
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10/13/15
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