The use of imatinib, an ABL tyrosine kinase inhibitor, has led to a dramatic change in the management of BCR-ABL-positive leukemia patients. However, resistance to imatinib mediated by mutations in the BCR-ABL domain has become a major problem in the treatment of these patients. »
04/04/13

Radiation mitigating effects of FLC in a mouse model of radiation pneumonopathy. »
04/04/13

Intake of preserved foods was positively associated with the incidence of epithelial ovarian cancer in southern Chinese women. »
02/28/13

The nab-PC treatment yielded promising results regarding the efficacy endpoint in NSCLC. »
01/15/13

There is relatively little methylation array data available specifically for oral squamous cell carcinoma (OSCC). This study aims to compare the DNA methylome across a large cohort of tumour/normal pairs. »
01/03/13

Immunomodulatory role for GPX3 that limits the development of colitis-associated carcinoma. »
12/05/12

Functional links existing between pseudopalisades, hypoxia, and tumor progression. »
11/29/12

Bacterial vaginosis (BV), the most common vaginal disorder among women of reproductive age, has been suggested as co-factor in the development of cervical cancer. Previous studies examining the relationship between BV and cervical intra-epithelial neoplasia (CIN) provided inconsistent and conflicting results. The aim of this study is to clarify the association between these two conditions. »
02/23/13

Experimental studies have established a causal connection between tumour hypoxia, hypoxia-associated proteome changes and downregulation of E-cadherin, the final common pathway of epithelial-to-mesenchymal transition (EMT). Our study aimed at elucidating the interrelationship of these processes in cancers of the uterine cervix in vivo. »
01/15/13

FasL expression and tumor immunoescape in cervical cancer could be CRH dependent. »
03/15/13