Purpose: To analyze of survival curve and toxicity outcomes for patients treated for nasopharyngeal carcinoma (NPC) by intensity-modulated radiotherapy (IMRT) delivered by helical TomoTherapy (HT). »
05/01/13

The eukaryotic translation initiation factor 5A1 (eIF5A1) is a highly conserved protein involved in many cellular processes including cell division, translation, apoptosis, and inflammation. Induction of apoptosis is the only function of eIF5A1 that is known to be independent of post-translational hypusine modification. In the present study, we investigated the involvement of mitogen- and stress-activated protein kinases during apoptosis of A549 lung cancer cells infected with adenovirus expressing eIF5A1 or a mutant of eIF5A1 that cannot be hypusinated (eIF5A1K50A). »
05/02/13

Malignant peripheral nerve sheath tumors (MPNSTs) are highly aggressive and associated with poor prognosis. Basic research to develop new treatment regimens is critically needed. »
05/04/13

Cigarette smoking is an independent predictor for patients with NMIBC. »
05/03/13

Dual inhibition of IL-6/IL-8 signaling as a therapeutic strategy to improve outcomes for TNBC patients. »
05/02/13

Neratinib and paclitaxel combination therapy demonstrated a high rate of response in patients with HER2-positive breast cancer. »
04/30/13

MiR-224 upregulation was associated with aggressive progression and poor prognosis in cervical cancer. »
03/25/13

KLK15 classical mRNA expression levels as a novel biomarker helpful for the differential diagnosis and prognosis of prostate cancer patients. »
09/13/12

Sustained aerobic exercise did not counteract the tumor-promotional effect of increased consumption of a high-fat diet, suggesting that diet is more influential in PCa progression than exercise. »
02/22/13

Sumoylation signaling may activate p53-mediated cell death in melanoma. »
04/30/13